pyridine, 4-fluoro-2-methyl-
4-fluoro-2-methylpyridine
CAS: 766-16-5
Molecular Formula: C6H6FN
pyridine, 4-fluoro-2-methyl- - Names and Identifiers
| Name | 4-fluoro-2-methylpyridine |
| Synonyms | 4-FLUORO-2-PICOLINE 4-FLUORO-2-METHYLPYRIDINE 4-fluoro-2-methylpyridine Pyridine,4-fluoro-2-methyl- pyridine, 4-fluoro-2-methyl- |
| CAS | 766-16-5 |
| InChI | InChI=1/C6H6FN/c1-5-4-6(7)2-3-8-5/h2-4H,1H3 |
pyridine, 4-fluoro-2-methyl- - Physico-chemical Properties
| Molecular Formula | C6H6FN |
| Molar Mass | 111.12 |
| Density | 1.077±0.06 g/cm3(Predicted) |
| Boling Point | 128-132℃ |
| Flash Point | 32.6°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 11.9mmHg at 25°C |
| Appearance | Liquid |
| Color | Colorless to pale yellow |
| pKa | 4.83±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
| Sensitive | Air Sensitive |
| Refractive Index | 1.4715 |
pyridine, 4-fluoro-2-methyl- - Introduction
4-fluoro-2-methylpyriridine is an organic compound with the chemical formula C6H6FN. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 4-fluoro-2-methylpyriridine is a colorless to pale yellow liquid
-Solubility: It can be dissolved in organic solvents such as ethanol and benzene, but insoluble in water
-Melting point:-58 ℃
-Boiling point: 148 ℃
-Density: about 1.10 g/ml
-Odor: Has an odor similar to pyridine
Use:
-4-fluoro-2-methylpyrridine is commonly used as an intermediate in organic synthesis and can be used to synthesize other compounds, such as pharmaceuticals, dyes, pesticides and organometallic complexes.
-It can also be used as a coordination reagent, which can form complexes with metal ions.
Preparation Method:
There are many synthetic methods of-4-fluoro-2-methylpyriridine. A common method is the reaction of 2-methyl-4-pyridinaldehyde and hydrogen fluoride in chloroform or trichloromethane to produce 4-fluoro-2-methylpyriridine.
Safety Information:
-4-fluoro-2-methylpyriridine is a flammable liquid, contact with open flame or high temperature may cause a fire.
-It is irritating to the skin and eyes. Personal protective equipment such as chemical protective gloves and goggles should be used when in contact.
-In use and storage need to take good ventilation conditions, and avoid inhalation of its steam.
-It should be kept away from heat sources, fire sources and oxidants, and stored in a sealed container, away from open flames and high temperatures.
-If an accidental leak, appropriate measures should be taken to clean up and deal with it.
Nature:
-Appearance: 4-fluoro-2-methylpyriridine is a colorless to pale yellow liquid
-Solubility: It can be dissolved in organic solvents such as ethanol and benzene, but insoluble in water
-Melting point:-58 ℃
-Boiling point: 148 ℃
-Density: about 1.10 g/ml
-Odor: Has an odor similar to pyridine
Use:
-4-fluoro-2-methylpyrridine is commonly used as an intermediate in organic synthesis and can be used to synthesize other compounds, such as pharmaceuticals, dyes, pesticides and organometallic complexes.
-It can also be used as a coordination reagent, which can form complexes with metal ions.
Preparation Method:
There are many synthetic methods of-4-fluoro-2-methylpyriridine. A common method is the reaction of 2-methyl-4-pyridinaldehyde and hydrogen fluoride in chloroform or trichloromethane to produce 4-fluoro-2-methylpyriridine.
Safety Information:
-4-fluoro-2-methylpyriridine is a flammable liquid, contact with open flame or high temperature may cause a fire.
-It is irritating to the skin and eyes. Personal protective equipment such as chemical protective gloves and goggles should be used when in contact.
-In use and storage need to take good ventilation conditions, and avoid inhalation of its steam.
-It should be kept away from heat sources, fire sources and oxidants, and stored in a sealed container, away from open flames and high temperatures.
-If an accidental leak, appropriate measures should be taken to clean up and deal with it.
Last Update：2024-04-09 02:00:48
